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The antigen receptors are small and are repelled by the large adhesion molecules.
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Cell Reports,DOI: The loose bond formed between the two cell surfaces allows for the binding of T-cell receptors to the presented antigen. Robert, Philippos Demetriou, Michael L.
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To do this, T-cells make contact with the antigen-presenting immune cells and read information from their surface. Fairmont Hotel Vier Jahreszeiten.
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Both cells form a ring-shaped structure made of different proteins at the point of contact between the cells — termed immunological synapse — over which they can exchange information.
Arbitration Drinks, Interactive Cooking and Dinner. Jingxia Shi, China Prof. ![]() Today, the researchers have published their results in the scientific journal Cell Reports. This cell type is responsible for classifying the presented parts as dangerous or harmless and, if necessary, initiating a response against them. To achieve this, however, immune cells must be able to recognise intruders and to classify them as dangerous or harmless. |
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The ring pattern is thus a result of mechanical forces in the cell membrane which sorts the molecules in the synapse according to their size.

To do this, T-cells make contact with the antigen-presenting immune cells and read information from their surface. Dustin to simulate the formation of synapses using computer models.
Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area.
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